Abstract: The project is located in the first level slop of Yangtze River and belongs to the slippery stratum.There had been adverse geologic phenomena like landslide and deformable body near it.After cutting slopes according to the construction scheme,the tableland is divided into three relatively high artificial slopes,and the high-rise buildings are located in each plain stage of all stages of side slopes and near to the slope top.After the construction of buildings is finished,under the influence of earthquakes,wind loads and vertical loads,there will be part of the horizontal force transmitted to the retaining structures through rock and earth mass of slopes,resulting in a increase of the surplus sliding force on retaining structures.Through combing theoretical formulas and numerical simulation method,this paper checks the overall stability of the slope and the local stability of artificial side slope,confirms the rationality of retaining scheme,analyzes the trend of architecture horizontal load's influence on the internal force of side slope retaining structure,proposes that the retaining structures should be designed to consider the adverse effects of building transmitting horizontal force and recommends to take measures such as strengthening the construction side piles,strengthening the rigidity of ground beams and additional tensile anchor on pile block to enhance the capacity of building itself to resist part of horizontal force.