Based on a series of 1D secondary consolidation tests for natural and remolded soft clay samples at Hexi region in Nanjing, the pre-pressure, the load ratios and the loading methods on secondary consolidation properties of remolded samples and deformation characteristics of the natural samples have been researched. The results show that the pre-consolidation pressure can significantly reduce the secondary consolidation coefficient when the consolidation pressure is less than pre-pressure. Otherwise, the effect of pre-pressure on the secondary consolidation coefficient is not obvious. Increase of the load ratios is able to increase the secondary consolidation coefficient. The corresponding secondary consolidation coefficient of the step loading is greater than the separate loading. The creep deformation of natural samples in the region has the character of decay slowly.