A complex landslide in Guangdong Province is analyzed as a typical engineering case. Combined with the field deformation survey, engineering geological mapping and supplementary deep hole displacement monitoring, the landslide is divided into different grades, layers and zones, and the landslide characteristics and causes are analyzed. It is considered that the comprehensive effects of geological environment, engineering activities, rainfall and groundwater lead to the slope landslide. According to the characteristics of the landslide, the technical scheme of "vertical steel pipe group piles + inclined prestressed anchor cable crown beam" is put forward, which can provide reference for the treatment of landslide under similar geological conditions.